The procedure usually takes around 30-60 minutes, depending on the location of the tissue being sampled. This includes setup and imaging time.

Local anesthesia is administered to numb the area, so you may feel pressure but should not experience pain. Mild soreness afterward is common but manageable with over-the-counter pain relief.

CT-guided biopsies are generally safe, but there’s a small risk of bleeding, infection, or injury to nearby structures. These risks are rare and are minimized by the use of imaging guidance.

Preparation varies depending on the area being biopsied. You may be asked to fast for a few hours before the procedure, and you should inform your doctor if you are taking blood thinners or have any allergies.