The HPE (Histopathological Examination) Lymph Node Test is a crucial diagnostic procedure used to examine lymph nodes for any abnormalities, such as infections, malignancies.
Lymph nodes are small, bean-shaped structures that play a vital role in the body’s immune system by filtering lymph fluid and trapping harmful substances like bacteria and cancer cells. This test helps healthcare providers understand the nature of any disease affecting the lymph nodes and guide appropriate treatment.
Lymph nodes are distributed throughout the body, and their swelling or enlargement can indicate a wide range of medical conditions. The HPE Lymph Node Test pune is particularly important for diagnosing:
1] Infections: Lymph nodes often swell in response to infections. The test can help identify the type of infection, whether bacterial, viral, or fungal.
2] Cancer: Enlarged lymph nodes can be a sign of cancer, either originating in the lymphatic system (lymphoma) or spreading from other organs (metastatic cancer). Histopathological examination is essential in confirming the presence of cancerous cells.
3] Autoimmune Diseases: Conditions like lupus or rheumatoid arthritis can also cause lymph node enlargement. The test can assist in understanding the underlying cause.
1. Sample Collection
The HPE Lymph Node Test pune typically begins with the collection of a lymph node sample. This can be done through:
1] Fine Needle Aspiration (FNA): A thin needle is inserted into the lymph node to extract cells for examination. This method is minimally invasive and can often be performed in an outpatient setting.
2] Excisional Biopsy: In cases where more extensive examination is required, an entire lymph node or a portion may be surgically removed under local or general anesthesia.
2. Laboratory Analysis
Once the sample is collected, it is sent to a laboratory where pathologists perform the histopathological examination. The steps involved include:
1] Tissue Processing: The lymph node sample is fixed in formalin to preserve its structure, followed by dehydration, embedding in paraffin, and sectioning into thin slices.
2] Staining: Special stains are applied to the tissue sections to highlight specific cells and structures, making it easier to identify abnormalities.
3] Microscopic Examination: Pathologists examine the stained slides under a microscope to look for abnormal cells, signs of infection, or malignancy.
3. Reporting Results
After the analysis, the pathologist prepares a report detailing the findings. This report will indicate whether the lymph node is normal, inflamed, or shows signs of infection or cancer.
1] Normal Results: If the lymph node is healthy, it will show normal architecture with no signs of malignancy or significant inflammation.
2] Reactive Lymphadenopathy: This indicates the lymph node is responding to an infection or inflammation but does not show cancer.
3] Lymphoma: If cancerous cells are detected, the report will specify the type of lymphoma and its grade, guiding treatment options.
4] Metastatic Cancer: The presence of cancer cells from another site can indicate advanced disease and will necessitate further evaluation.
At Diagnopein offer blood test pathology lab centre for comprehensive, accurate, and timely diagnostic services, including the HPE Lymph test Pune. With our NABL-accredited labs, cutting-edge technology, and skilled technicians, you can be assured of reliable results every time. Get your results quickly, especially when time is crucial in detecting severe infections.
Competitive pricing without compromising on quality. Our team of experienced professionals ensures the test is conducted smoothly with minimal discomfort. We provide not just the HPE Lymph test results but insights into your health condition, helping you and your doctor make informed decisions about treatment. For more information call us at +91 9204 108108.
Risks are minimal but may include bleeding, bruising, or infection at the biopsy site. For excisional biopsies, there may also be a risk of scarring or reaction to anesthesia.
The HPE Lymph test involves minor discomfort depending on the method used for sample collection. Fine Needle Aspiration is minimally invasive and typically less painful than an excisional biopsy, which may require local or general anesthesia.
For Fine Needle Aspiration, a thin needle is inserted into the lymph node to collect cells. In an excisional biopsy, a small incision is made to remove a part or the entire lymph node. The sample is then sent to a laboratory for histopathological examination.
For an excisional biopsy, your doctor may ask you to avoid eating or drinking a few hours before the procedure. For Fine Needle Aspiration, little to no special preparation is usually needed.
