Antigliadin IgM Antibodies is a blood test that detects antibodies against gliadin, a protein found in wheat.
Antigliadin IgM antibodies are immune proteins produced in response to gliadin. These antibodies can be elevated when the body perceives gliadin as a threat, leading to an immune response that may damage the intestines or cause symptoms in people with gluten sensitivity or celiac disease.
This ANTIGLIADIN IGG ANTIBODIES test is crucial for individuals who may be experiencing symptoms that suggest gluten sensitivity, such as digestive issues, fatigue, or malabsorption. The Gliadin Antibody Test provides insights into whether the immune system is reacting to gluten, helping guide dietary and treatment decisions.
Understanding the specific antibody levels and their meanings can help determine how the body is responding to gluten.
Gliadin Antibody Test Range
The gliadin antibody test range varies based on antibody type (IgA, IgM, IgG) and lab standards. However, generally:
Normal Range: Typically below 20 U/mL for most gliadin antibody tests, though specific ranges may differ between labs.
Elevated Levels: Above 20 U/mL often suggests a heightened immune response, indicating potential gluten sensitivity or celiac disease.
When gliadin IgG levels are high, it indicates that the immune system is reacting to gluten. High IgG levels, particularly when other antibodies are also elevated, can point toward gluten sensitivity or celiac disease. If Gliadin IgG is high while tTG (tissue transglutaminase) is negative, this may indicate gluten sensitivity without confirmed celiac disease.
Secretory Immunoglobulin A (SIgA) is another marker in immune testing, often found in the intestines and mucosal linings. High anti-gliadin SIgA levels may indicate an immune response localized in the gut, even if serum levels are normal, suggesting gluten sensitivity that could contribute to digestive symptoms.
Gliadin positive, tTG negative results can be confusing. A positive gliadin antibody test with a negative tTG (tissue transglutaminase) antibody test suggests gluten sensitivity rather than celiac disease. tTG is more specific to celiac disease, while gliadin antibodies may simply indicate a reaction to gluten without full-blown autoimmune damage to the intestines.
Choosing Diagnopein in Pune for your antigliadin IgM antibodies test provides a reliable, thorough diagnostic experience. Here are several reasons why Diagnopein is the preferred choice:
1. NABL-Certified Lab: Diagnopein adheres to NABL (National Accreditation Board for Testing and Calibration Laboratories) standards, ensuring high-quality testing with accuracy and reliability.
2. Advanced Diagnostic Equipment: Equipped with the latest technology, Diagnopein uses advanced immunology instruments to provide precise and detailed results.
3. Experienced and Trained Staff: Our skilled technicians and healthcare professionals are well-versed in immunology testing, offering expertise in interpreting and explaining test results.
4. Affordable Pricing: Diagnopein offers competitive pricing for advanced testing, making it accessible for individuals seeking quality healthcare without excessive costs.
5. Hygienic and Comfortable Facilities: We maintain clean and safe environments across all facilities, ensuring patient comfort and safety.
6. Quick and Accurate Results: Diagnopein prioritizes timely reporting, ensuring that results are delivered promptly for efficient decision-making.
7. Comprehensive Consultations: Our team offers personalized guidance on test results, helping you understand your results and explore potential dietary and medical steps.
Yes, antibody levels can fluctuate depending on gluten intake. Following a gluten-free diet may result in decreased antigliadin antibody levels over time.
Often, tissue transglutaminase (tTG) and anti-endomysial antibodies (EMA) tests are recommended alongside gliadin testing, especially in suspected celiac disease cases.
Typically, fasting is not required for this test. However, it is advisable to follow any specific instructions provided by your healthcare provider.
Gliadin IgA antibodies tend to reflect immune responses in the intestines, while gliadin IgG indicates a general immune reaction to gluten, both relevant in diagnosing gluten sensitivity and celiac disease.
High antigliadin IgM levels indicate an immune response to gluten, which can suggest gluten sensitivity or celiac disease, particularly when accompanied by symptoms or elevated IgG and IgA levels.
