Anti-Thrombin III is a protein in the blood that plays a crucial role in regulating blood clotting.
The Anti-Thrombin III test measures the amount of AT III protein in the blood to help identify deficiencies or abnormalities that can lead to blood clotting disorders. Testing AT III levels is often recommended for patients with unexplained blood clots or those with a family history of Antithrombin III deficiency.
Normal Range (Reference Value): The normal range of Anti-Thrombin III in adults is typically between 80-120%. This percentage represents the activity level of AT III compared to standard clotting activity.
High Anti-Thrombin III: High levels of AT III are less common and may be linked to certain inflammatory conditions, liver disease, or hormone therapy, but they generally do not pose a high risk for clotting issues.
Low Anti-Thrombin III: Levels below 80% suggest Antithrombin III deficiency, which can increase the risk of clot formation and may warrant further evaluation and treatment.
Decreased levels of AT III can result from various factors, including genetic and acquired causes:
Genetic Deficiency: Hereditary Antithrombin III deficiency is an inherited disorder that leads to low AT III levels, increasing the risk of blood clots.
Liver Disease: Since AT III is produced in the liver, liver dysfunction or liver disease can reduce its production.
Disseminated Intravascular Coagulation (DIC): This condition, which involves abnormal blood clotting throughout the body, can lead to decreased AT III levels.
Kidney Disease: Conditions such as nephrotic syndrome cause protein loss through urine, which may lower AT III levels.
Acute Infections and Inflammation: Severe infections or inflammatory states can consume clotting factors, leading to lower AT III activity.
Medications: Heparin therapy can reduce AT III levels since AT III is used up during heparin administration.
The AT III test is recommended for individuals who:
Have experienced unexplained blood clots.Have a family history of Antithrombin III deficiency or other clotting disorders. Show symptoms of liver disease or other conditions affecting blood coagulation. Are undergoing prolonged heparin therapy.
Choosing Diagnopein Diagnostic Center for your Anti-Thrombin III Test in Pune means opting for quality care, reliable results, and an excellent patient experience. Here’s why Diagnopein is a preferred choice:
1. NABL Certified Lab: Diagnopein’s NABL accreditation ensures the highest quality standards and accurate results.
2. Advanced Technology: We utilize cutting-edge technology for precise testing and reporting.
3. Experienced Staff: Our team is well-trained and experienced in handling specialized tests, including the AT III test.
4. Affordable Cost: Diagnopein provides competitively priced testing services, making healthcare accessible.
5. Clean & Hygienic Environment: Our facility is maintained with strict hygiene standards, offering a comfortable experience.
6. Fast Turnaround: We prioritize timely reporting so you can discuss results with your healthcare provider promptly.
Low levels can result from genetic deficiencies, liver disease, nephrotic syndrome, DIC, infections, or prolonged heparin therapy.
Generally, fasting is not required for the AT III test, but consult with your healthcare provider for specific instructions.
Diagnopein typically provides test results within a few days, allowing for quick follow-up.
The AT III test assesses AT III protein levels in the blood, helping to diagnose clotting disorders such as Antithrombin III deficiency.
Yes, heparin and certain other medications can affect AT III levels, so inform your healthcare provider about any current medications.
High AT III levels are less common and are typically not associated with an increased risk of clotting. They may, however, indicate an inflammatory or liver condition.
