The double marker blood test measures the levels of two specific proteins in the blood like Beta hCG (Human Chorionic Gonadotropin) and PAPP-A (Pregnancy-Associated Plasma Protein-A).
The Double Marker Test is a vital prenatal screening tool that helps assess the risk of chromosomal abnormalities in the fetus during pregnancy. It is usually performed during the first trimester of pregnancy, typically between the 9th and 13th weeks. Double Marker Test in Pregnancy is often part of a broader screening process known as the first-trimester screening, along with an ultrasound scan for nuchal translucency.
The double marker test results are expressed as a risk ratio, which represents the likelihood of the fetus having a chromosomal abnormality. The test uses a combination of the mother's age, blood test results, and ultrasound findings to calculate the risk.
1] Low Risk: A low-risk result indicates that it is unlikely that the fetus has chromosomal abnormalities. However, a low-risk result does not eliminate the possibility entirely.
2] High Risk: A high-risk result suggests a higher likelihood of chromosomal abnormalities, and further diagnostic tests, such as amniocentesis or chorionic villus sampling (CVS), may be recommended.
It's important to understand that the double marker test results do not provide a definitive diagnosis. Instead, they offer an assessment of risk, which may help guide further decisions about more invasive testing.
The double marker normal range varies depending on various factors, including the gestational age and maternal health. However, in general, normal levels for the two markers are:
1] Free Beta hCG: In a normal pregnancy, the levels of Free Beta hCG may range from 2570 - 108,000 mIU/ml during the first trimester.
2] PAPP-A: Normal levels of PAPP-A (Pregnancy-Associated Plasma Protein-A) during the first trimester range from approximately 0.79 – 6.01 mIU/mL.
When these values are within the double marker test normal values, the risk of chromosomal abnormalities is considered low. If the values are significantly outside these ranges, further investigation may be warranted.
You should choose Diagnopein for your DOUBLE MARKER test because we are committed to providing high-quality diagnostic care in a clean and hygienic environment. Our center is equipped with advanced technology to ensure accurate and reliable test results, which are crucial for assessing this test. Diagnopein’s experienced staff is dedicated to handling tests with precision and care, offering you both expertise and comfort. We also offer affordable pricing, making essential health diagnostics accessible without compromising quality. For timely, professional, and affordable cardiac testing, Diagnopein is your trusted partner for your healthcare.
1. Free Beta HCG
2. PAPPa (Pregnancy Associated Plasma Protein)
3. Risk factor calculated by
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This double marker test is typically done in the first trimester of pregnancy (between 9 to 13 weeks) to screen for potential genetic conditions and chromosomal abnormalities in the fetus. It helps guide decisions about further diagnostic tests.
Free Beta hCG: A hormone produced by the placenta during pregnancy. PAPP-A (Pregnancy-Associated Plasma Protein A): A protein produced by the placenta in early pregnancy.
Double Marker Pregnancy Test is simple and involves drawing a small blood sample from the mother’s arm. The sample is sent to a laboratory, where the levels of Free Beta hCG and PAPP-A are measured and analysed.
No, a high-risk result does not confirm that your baby has a chromosomal condition. It only indicates a higher probability, and further diagnostic testing is recommended to confirm any potential abnormalities.
