The Anti-Gliadin IgG Antibodies test is a blood test used to detect the presence of antibodies produced by the immune system in response to gliadin, a protein found in gluten.
Gliadin is one of the components of gluten. When a person with an autoimmune disorder like Celiac Disease or non-celiac gluten sensitivity ingests gluten, the immune system mistakenly identifies gliadin as harmful and produces antibodies against it. These antibodies are known as Anti-Gliadin IgG antibodies.
IgG (Immunoglobulin G) is the most common antibody in the blood and is responsible for the immune system’s response to infections. In the case of gluten sensitivity or Celiac Disease, the presence of these antibodies can indicate an immune response to gluten ingestion, which may lead to damage in the intestines or other symptoms.
1] Celiac Disease: Celiac disease is an autoimmune disorder where the ingestion of gluten leads to inflammation and damage to the small intestine, impairing nutrient absorption. This can lead to a variety of gastrointestinal symptoms (like diarrhea, abdominal pain, and bloating) and non-gastrointestinal symptoms (such as fatigue, joint pain, and skin rashes). Testing for Anti-Gliadin IgG antibodies helps detect this immune response.
2] Non-Celiac Gluten Sensitivity: This is a condition where individuals experience symptoms similar to Celiac Disease, such as digestive discomfort, bloating, fatigue, and headaches, but without the autoimmune damage or antibodies associated with Celiac Disease. While not a diagnostic criterion for gluten sensitivity, elevated Anti-Gliadin IgG antibodies may indicate a sensitivity to gluten.
1] Positive Results: A positive result for Anti-Gliadin IgG antibodies suggests that the individual’s immune system is reacting to gluten. It is often associated with Celiac Disease or non-celiac gluten sensitivity. However, a positive result does not definitively diagnose either condition. In the case of Celiac Disease, additional tests are required to confirm the diagnosis, such as:
A] Anti-tissue transglutaminase (tTG) antibodies test
B] Endoscopy with a biopsy of the small intestine
In some cases, elevated Anti-Gliadin IgG levels may indicate gluten sensitivity rather than Celiac Disease, especially if the person’s symptoms do not meet the criteria for Celiac Disease.
2] Negative Results: A negative result for Anti-Gliadin IgG antibodies generally suggests that gluten is not triggering an immune response. This may mean the person does not have Celiac Disease or gluten sensitivity, though it is not always definitive. Some individuals with gluten intolerance may have low or undetectable levels of Anti-Gliadin IgG antibodies.
You should choose Diagnopein for your ANTIGLIADIN IGG ANTIBODIES test because we are committed to providing high-quality diagnostic care in a clean and hygienic environment. Our center is equipped with advanced technology to ensure accurate and reliable test results, which are crucial for assessing this test. Diagnopein’s experienced staff is dedicated to handling tests with precision and care, offering you both expertise and comfort. We also offer affordable pricing, making essential health diagnostics accessible without compromising quality. For timely, professional, and affordable cardiac testing, Diagnopein is your trusted partner for your healthcare.
his test helps in the diagnosis of Celiac Disease and non-celiac gluten sensitivity. It can reveal an immune reaction to gluten, which may cause symptoms like abdominal discomfort, fatigue, and bloating.
The test is performed by drawing a small sample of blood from a vein in your arm. The sample is then sent to a laboratory where it is analyzed for the presence of Anti-Gliadin IgG antibodies. The test can be done while you are still consuming gluten in your diet for accurate results.
The Anti-Gliadin IgG test is primarily used to diagnose Celiac Disease and non-celiac gluten sensitivity. It may also be elevated in individuals with other autoimmune conditions like Hashimoto's thyroiditis, rheumatoid arthritis, or type 1 diabetes, though this is not diagnostic.
No special preparation is needed, but it is important to continue consuming gluten in your diet until the test is done. Avoiding gluten can lead to a drop in antibody levels, which may result in false-negative results.
